Web Avatars: Erasmus and Kinkajou
DR Xxxxx : Case 7: Comments 4
E&LFTs:
Note serum uric acid 0.38 (RR 0.25-0.50): This is in the high normal range. It suggests possible early renal dysfunction (in pre-significant or a preclinical stage) or high white cell turnover or both.
Creatinene 0.08 (RR 0.03-0.09): possible just a little high for a young man of 16. In Dr. Xxxxx’s experience well young men typically have levels at 0.06 – 0.07
Antigliaden IgG 0.79 (RR<1.00)
Antigliaden IgA 0.28 (RR <1.00):
Note that since laboratories have moved to using a deamidated antigen kit for testing , this test is almost useless in assessing mild or moderate grades of wheat / gluten allergy / intolerance.
The Paill Spectrum model suggests that any antigliaden antibody level greater than 20-25% of reference range as calibrated for endoscopically proven Celiac disease, is likely to have significant health effects on the patient, both directly and indirectly. Wheat antibodies (anti-gliaden antibodies) trigger low-grade malabsorption problems sufficient to affect vitamin and mineral uptake. They also affect antigen processing probably at the TAP protein level, causing the immune response to other antigens to be smoke screened by the continued presence of wheat antigen. (Also known as gliaden or gluten).
Serum Zinc 13.1 (RR 12.0-28.0)
The patient would benefit from having their zinc levels raised. This is a slow difficult process, complicated by poor zinc bioavailability and exacerbated by the wheat allergy / gluten intolerance.
RBC Folate: 542 nM =238 mcg/ml
The patient will do better if this level is at least 250- 300 mcg/ml. One of the Australian vitamins has very good clinical effects on tiredness, probably largely from its extra high folic acid levels.